The village of Lykovo, founded by merchant Lykov in the 16th century, belonged to the Kozmina-Yakhromsky Monastery until 1764. In 1823, a stone church dedicated to the Intercession of the Holy Virgin was built on the site of wooden churches dedicated to Saint Nicholas the Wonderworker and Great Martyr George the Victorious. Construction began in 1811 based on an approved project, and the consecration of the chapels in honor of St. Nicholas and St. George took place in 1816. The full consecration of the church occurred on October 1, 1823, under the guidance of Archbishop Parfeny of Vladimir.

In 1838, the church was adorned with magnificent frescoes that have survived to this day. The church impresses with its size: its area is 1500 sq. m, and its height with the cross reaches 40 m. The iconostasis of the main church, made in the Empire style, astonishes with the elegance and richness of its carved details and icons. During the Soviet era, the church remained open and was preserved thanks to the efforts of local residents.

On August 20, 2007, lightning damaged the spire of the bell tower and the internal ceilings. In June 2010, a new spire was lifted by helicopter and installed in its original place.

The architecture of the church is in the classical style. The central part is a two-story classical cube with a massive octagonal lantern, decorated with pediments, on which rises a spherical dome with an onion-shaped head on an additional drum. A spacious rectangular refectory adjoins from the west, along with a three-tiered bell tower topped with a high metal spire. To the east, there is a small five-sided apse. The external finishing of the facades is characterized by simplicity and conciseness.