The history of the Kizel parish is closely intertwined with the history of the city of Kizel and the noble family of Lazarevs, who owned these lands from 1778 to 1918. Their mining estate was one of the largest in the Urals and included factories, mines, and vast lands.

With the acquisition of land by the Lazarevs, the region began to develop actively. On July 3, 1788, a cast iron and ironworking plant was established on the banks of the Kizel River, and soon the first chapel appeared, which was consecrated as a church in 1803. Between 1805 and 1808, a second church was built in honor of the Holy Life-Giving Trinity. From 1861 to 1871, with the funds of the princes Lazarev and Abamelek-Lazarev, the stone Holy Trinity Cathedral was erected, becoming the center of spiritual life in the district.

Kizel developed thanks to its natural resources, attracting people from the surrounding areas. For their spiritual needs, several churches and chapels were built in the 19th and 20th centuries. However, with the arrival of the Bolsheviks, churches began to close, and on the night of April 29 to 30, 1932, the Holy Life-Giving Trinity Cathedral was blown up. The lands and valuables of the parish were plundered, and clergy were subjected to repression.

By the beginning of the Great Patriotic War, there were no functioning churches in the area. In 1944, due to a weakening of the persecutions, activities resumed in the Nikolaev Chapel. On the foundation of the Holy Trinity Cathedral, the Kizel Drama Theater was built, which moved to Chaykovsky in 1982.

On June 10, 1994, the building of the former Pioneer House was transferred to the Russian Orthodox Church. On August 3, 1994, the Diocesan Council supported the restoration of the building. In 1996, the Holy Altar was consecrated in the Holy Nicholas Church, and in 1999, part of the church land was returned. In 2001, the main chapel in honor of St. Nicholas was consecrated, and in 2005, the construction of the bell tower was completed.