On October 25, 1908, the Kazan Icon of the Mother of God Church was consecrated in Perm, with construction beginning on May 1, 1905. The brick church, dedicated to the Kazan Icon of the Mother of God, was built on the grounds of the Holy Assumption Women's Monastery to replace an earlier wooden church. The funds for construction were provided by Ivan Grigoryevich and Vera Alexandrovna Kamensky, long-time benefactors of the monastery.

The author of the church's design is unknown, but researchers suggest it could have been Yu. Skavrovsky, V.M. Vasnetsov, or V.A. Pokrovsky. Artists S.I. Vashkov, who created the wooden carved iconostasis and sketches of the utensils, and N.K. Roerich, who painted icons for the iconostasis, participated in the church's decoration. It is also possible that N.K. Roerich is the author of the majolica panels "Kazan Mother of God" on the eastern and "Christ the Almighty" on the northern facades of the church.

In the church's basement, a family burial vault was planned, where only I.G. Kamensky was buried in 1919. Later, his remains were moved, but information about the new burial site is unavailable.

In 1918, all buildings of the monastery were municipalized. In 1921, the church, recognized as a work of art, along with its utensils, iconostasis, and icons, was transferred to the Perm State Museum. In 1922, all movable property was included in the collections of the new Art Gallery. In 1933, the monastery buildings were located in the area designated for a military unit. In the post-war years, residential and social construction began on the territory of the former monastery. Since 1960, the Kazan Church building was used as a warehouse. By this time, the domes, bell tower, and burial site of I.G. Kamensky had been lost, and the majolica panels were severely damaged.

In 1969, the building was included in the list of historical and cultural monuments of local significance, and in 1974, it received the status of a monument of republican significance. In 1985, the building was transferred to the regional local history museum, which began its restoration. In 1995, the church was granted indefinite free use to the newly established Holy Assumption Women's Monastery.

The church is located in the center of the block, in the western part of the former Assumption Women's Monastery estate. It has a brick structure, square in plan with a semicircular apse and a basement where a crypt is arranged. The corners of the building are reinforced with stone buttresses. The western entrance is decorated with a limestone portal, and above the arched doorway is a metal canopy on forged brackets. Other facades are designed in the same style, including a triple arched window on the southern facade and the apse with a majolica depiction of the Kazan Mother of God in a shaped limestone frame.

On the northern facade, on a rectangular pilaster, there is a single-tier open bell tower with a gable roof topped with a round drum and a simple cross. Under the bell arch is a niche with remnants of the majolica panel "Christ the Almighty." The temple is covered with a four-pitched roof and topped with a large dome with a cross on a round blind drum with arcading around the perimeter. The arcading, pilasters, icon frames, portal, and base are made of local limestone. The interior space of the temple is covered with a high vaulted ceiling, and the apse is conch-shaped. The walls and vault are plastered and whitewashed.