The village of Brilyakovo was founded in the mid-17th century when these lands belonged to the boyar Semyon Lukyanovich Streshnev. At that time, the first wooden church "In the Name of the Most Holy Theotokos of the Caves" was built here. According to legends, the Venerable Makary of Zheltovodsk stopped in these places. In the 19th and 20th centuries, the village was called Makary. Initially, it was mainly inhabited by church servants, and there were only two beggar households and three peasant households. This information is contained in the watch book of 1666, a copy of which is kept in the Central Archive of the Nizhny Novgorod Region. The book states that on June 6, 1666, in the Gorodets volost, belonging to boyar Streshnev, peasants and beggars settled on new lands, cleared the forests, and plowed the fields. The village of Brilyakovo was founded anew, and a tent-shaped church "In the Name of the Most Holy Theotokos of the Caves" was built, where the Venerable Makary of Zheltovodsk and the Unzhensky Miracle Worker served. The church housed local icons, vestments, and all kinds of church utensils, and there were bells in the belfry. Among the residents were priest Grigory Petrov with children, priest Gavrilo Semyonov, deacon Senka Stepanov with his brother, sexton Ivashka Zakhariev, prosphora-baker Paraskovitsa Pavlova with children, as well as several beggar and peasant households.

In 1741, the parishioners built and consecrated a cold wooden church in honor of the Annunciation of the Most Holy Theotokos with a wooden porch. In 1822, a stone church was erected next to it in honor of the Kazan Icon of the Mother of God, with a stone bell tower and a side chapel in the name of the Venerable Makary of Zheltovodsk and the Unzhensky Miracle Worker. The roof was covered with iron.

In the early 20th century, the parish had about 1000 people, with one full-time cleric and a psalmist. In 1928, the church was valued at 15,000 rubles, and technical drawings were made. In the 1930s, there was no full-time priest in the church, the wooden church became dilapidated and partially collapsed.

In 1938-1939, the building of the Kazan Icon of the Mother of God Church was converted into an outpatient clinic, an additional floor was added, and a doctor lived on the second floor. Parish life began to revive in 1999 when the first parish meeting took place on August 6. On November 29, 2000, the Kazan Church was transferred to the Nizhny Novgorod Diocese, it was consecrated again, and restoration work began. Since 2001, services have been held in the winter church, the Makary Chapel, and since 2005, the summer Kazan church has been in operation.