Thousands of Russian emigrants were scattered around the world first due to the Civil War and then World War II. In the late 1940s, some captured Red Army soldiers and displaced persons refused to return to the USSR, fearing persecution for having been in Nazi camps. Fortunately, hundreds of refugees found shelter, including in the USA, where some settled in Boston.

In 1953, they decided to create an Orthodox church. For a long time, they searched for a suitable building and settled on an abandoned Protestant church. However, a financial problem arose: they asked for 900 dollars, which was a significant amount at that time. Each family had to contribute 30 dollars, which was no small sum considering the lack of wealth in the Orthodox community. To raise the money, even skilled builders and medical workers worked evenings in restaurants and as night watchmen. Nevertheless, within a few months, the necessary amount was raised.

After that, the entire congregation enthusiastically set to work. Since all the money went to the purchase, they had to do the repairs and setup themselves. Among the migrants were carpenters, joiners, and electricians. An altar was built, and a legless soldier forged a candlestick from copper and carved a cross for the Gospel. In May 1955, the church opened its doors. The Epiphany Church quickly became a spiritual center for Russian-speaking residents. However, this did not last long.

By the 1970s, the area saw an increase in robberies and assaults, and many parishioners began to fear attending services. They had to look for a new building for the church. Today, the congregation numbers several thousand people, including descendants of the second wave of migration, immigrants from the USSR who arrived in the 90s, and native Americans.