The architectural complex located in the city center includes monuments of varying artistic value. Among them, the Epiphany Church stands out as the oldest surviving building in Galich. The first mention of it dates back to the first half of the 17th century. The land registry book of 1635 mentions two wooden parish churches: the Epiphany Church with a Nicholas chapel and the George Church with a chapel of Zosima and Savvatiy. In 1683, permission was granted to build a brick warm church with altars of Nicholas the Wonderworker and George the Victorious on the lower floor, as well as Epiphany and Zosima and Savvatiy on the upper one. By 1687, the building was likely completed, as the patriarch ordered the consecration of the 'newly built churches of the Epiphany and Nicholas the Wonderworker.' However, in 1687, only the lower church was consecrated, as the upper one was not yet finished. Its consecration took place only in 1710. In the early 18th century, the walls of the second floor of the church's apse were altered. To the west stood a tented bell tower, likely built simultaneously with the church. The second Epiphany Church, a cold one, was built in 1758 south of the bell tower. It featured a tiered composition with two light octagons on a high square and decor reminiscent of 17th-century traditions. After the construction of the cold church, the altar of the Epiphany was moved from the warm church, but the old church continued to be called the Epiphany Church, despite the fact that its main altar became that of Nicholas the Wonderworker.

Literary sources from the 19th and early 20th centuries mention the existence of a monastery here in the 18th century: some speak of a male monastery, others of a female one with a charitable institution. The building of the women's charitable institution, located on the southern side of the church territory, was built with the funds of merchant M.A. Redkin between 1839 and 1842 and opened in 1855. The patron was merchant P.G. Vakorin. In the southeastern part of the building was a church shop. A lodge, built in the late 19th and early 20th centuries, was located on the northwestern side of the church. In the 1930s, the cold church and bell tower were demolished, and the architecture of the warm church was significantly altered. However, in the 1970s and 1980s, architect V.S. Shaposhnikov restored its original appearance during renovations, restoring the five domes and the decor of the lower tier.

In 2008, specialists from the OGU 'Heritage' conducted research on the Epiphany Church and archaeological excavations under the guidance of A.G. Avdeev. It was suggested that the church originally looked different: along the northern wall was a one-story gallery, to which an apse was attached that extended beyond the wall of the square. A stone external staircase led to the second floor. During the excavations, the foundations of the northern apse, the gallery, and part of the foundations of the stone porch were discovered.