The name of the street Syromyatnicheskaya appeared in the late 18th and early 19th centuries and is associated with the Syromyatnichesky palace stable settlement, founded in the 16th century. Here lived craftsmen who made horse harnesses from rawhide.

At the intersection of Lower Syromyatnicheskaya Street and Syromyatnicheskaya Embankment, on the banks of the Yauza River, was the tea packaging factory of one of the largest Russian tea companies, "Gubkin, Kuznetsov and Company."

This company was one of the most profitable in the empire and had worldwide fame. It began its activities in 1840 by trading tea at the Nizhny Novgorod and Irbit fairs. Founded in the city of Kungur in the Perm province by merchant A.S. Gubkin, who was the first to sell tea in colorful packaging. In 1882, the administration moved to Moscow, and in 1884, the founder's grandson, A.G. Kuznetsov, transformed it into the Partnership "Successor of Alexey Gubkin A. Kuznetsov and Co." In 1891, a joint-stock company was created with a capital of 10 million rubles, which owned a sugar factory in Sokolniki until 1899. In 1895, a tea packaging factory opened on Lower Syromyatnicheskaya, becoming the company's main asset. The factory employed over 800 people and processed up to 100,000 poods of tea per year, ranking among the largest enterprises in Moscow. Over 15 years, the firm sold tea and sugar worth 300 million rubles within the Empire alone. The partnership opened branches in various cities across Russia and showcased its products at the largest global tea markets, including China, India, Ceylon, Java, and London. The trademark was "Two Anchors," symbolizing the highest quality of the product.

During the Soviet era, all company assets were nationalized and merged into "Tsentrochai." Now, in the former buildings of the Partnership, there are a magnetron and running wave lamp factory "Pluton," a non-profit partnership "Wikimedia RU," and part is used as a modern space ARTPLAY. Lower Syromyatnicheskaya Street remains one of the largest industrial zones, actively developing and gaining new life.

The ensemble of buildings was constructed in a unified architectural style, despite being built by different architects and at different times. Building 1 was designed by Moscow architect Pyotr Vikentyevich Kharko in the Art Nouveau style, while factory building number 2 was constructed in 1913 by Karl Karlovich Gippius.